The PIRCHE Risk and Acceptable Mismatch Profile provides you insights for every potentially mismatched allele, so you can evaluate each allele’s impact on the overall PIRCHE score. Allele frequencies help you in estimating frequent high-risk alleles. Import mean fluourescence intensities of your single antigen bead assays to overlay PIRCHE and MFI in a single bar chart. Select forbidden mismatch alleles and immediately see the impact on average epitope match grades and donor frequency. Never has it been easier to define unacceptable mismatches
The HSCT Search Profile is capable of matching 9/10 matched unrelated virtual donors with your patient. This information can guide your donor search by knowing the limits of minimal PIRCHE scores to be expected in a certain population. So you better know, if you may want to search for a specific mismatch-donor in other registries.
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