In the ULISES Project, we aim at developing an immunologic-based treatment strategy where cancer cells are “reprogrammed” to become “visible” to the patient’s own immune system, which will see them as “not belonging to the body” and will attack them, emulating the allogenic response to incompatible transplants. Thus, it will constitute a “natural” treatment, as the patient’s own immune system will be used to attack cancer cells, with no drugs, chemotherapy, radiotherapy, transplants, etc., significantly reducing the treatment time to few weeks and producing minimal or almost null side effects. In addition, this “reprogramming” will lead to an “immunological-memory” avoiding future relapses (vaccine-like effect) through TIL (Tumour Infiltrating Lymphocytes) generated around the tumour microenvironment by the immune system.
Consortium Partners:
- Consorci Institut D’Investigacions Biomediques August Pi i Sunyer (Spain)
- Victor Pallaruelo-Santamaria (Spain)
- Leids Universitair Medisch Centrum (Netherlands)
- Universitair Medisch Centrum Untrecht (Netherlands)
- Fundación para la Formación e Investigación Sanitarias de la Región de Murcia (ES)
- Fundación Instituto Valenciano de Oncología (Spain)
- PIRCHE AG (Germany)
- Universitat Politecnica De Valencia (Spain)
- Fondazione ICONS (Italy)
