Resources
Imagine a world where every decision you make is backed by the most advanced, personalized medical insights.
With Pirche, you have the power to transform lives, offering your patients the best chance at a healthier, happier future. Our technology supports you every step of the way, ensuring that your expertise is amplified by the latest scientific advancements.
Santos et al concluded a low PIRCHE score can help rule out development of harmful antibodies 94.2% of the time.
In deceased donor allocation, Niemann et al estimated that up to 25% of transplanted patients can be transplanted with a lower immunologic risk.
With a high PIRCHE score, Geneugelijk showed there is a 50% increase risk in kidney graft failure within 10 years.
Lachmann et al. demonstrated PIRCHE scores stratify immunologic risk in kidney transplanted patients.
timeline of key milestones
Education, training & Webinar
The Pirche Academy is your source of educational material around PIRCHE. We offer live webinars, recordings, tutorials, and documents
NOW PLAYING
Webinar 2019 E4: HSCT Search Profile
DESCRIPTION
Episode 4 of our Webinar Series 2019
In this episode we cover:
- How to load data into the input fields
- How to apply the PIRCHE stem cell donor search profile
- How to read the PIRCHE result page
E4: HSCT Search Profile
NOW PLAYING
Episode 7 of our Webinar Series 2019
DESCRIPTION
In this episode we cover:
- How to apply the PIRCHE batch matching modules
- How to read generated files in R and plot PIRCHE scores
E7: Batch Matching
NOW PLAYING
Episode 6 of our Webinar Series 2019
DESCRIPTION
In this episode we cover:
- How to upload Custom Population to the PIRCHE platform
E6: Custom Populations
NOW PLAYING
Episode 5 of our Webinar Series 2019
DESCRIPTION
In this episode we cover:
- How to load data into the input fields
- How to apply the PIRCHE RAMP module
- How to read the PIRCHE result page
E5: Risk and Acceptable Mismatch Profile
NOW PLAYING
PIRCHE Low Resolution SOT Matching - Webinar Series 2019 E3
DESCRIPTION
Episode 3 of our Webinar Series 2019
In this episode we cover:
- How the PIRCHE modules impute high-resolution typings based on given low-resolution input HLA typing
- How to load data into the input fields
- How to apply the PIRCHE solid organ transplantation module with low-resolution HLA typings
- how to read the PIRCHE result page
E3: Low Resolution SOT Matching
NOW PLAYING
PIRCHE High Resolution SOT Matching - Webinar Series 2019 E2
DESCRIPTION
Episode 2 of our Webinar Series 2019
In this episode we cover:
- How to load data into the input fields
- How to apply the PIRCHE solid organ transplantation module with high-resolution HLA typings
- How to read the PIRCHE result page
E2: High Resolution SOT Matching
NOW PLAYING
Webinar 2019 E1: HSCT Single Patient Matching
DESCRIPTION
Episode 1 of our Webinar Series 2019
In this episode we cover:
- How to load data into the input fields
- How to apply the PIRCHE stem cell transplantation module
- How to read the PIRCHE result page
E1: HSCT Single Patient Matching
NOW PLAYING
Webinar 2018 E1: Introduction and Overview
DESCRIPTION
In the first Webinar of our series, we give an overview about the PIRCHE matching technology and its application in stem cell transplantation and solid organ transplantation. We pinpoint the most important publications and how the algorithm is translated into a useable toolsuite. In the second half, we dive into the web app giving you an overview of how to use the service.
Introduction And Overview
NOW PLAYING
Webinar 2020-05: “Epitope Matching: There is no Excuse” (In Collaboration with Omixon)
DESCRIPTION
In this presentation, Matthias Niemann, Technical Director of PIRCHE, explains the ways of HLA allorecognition and shows the differences between the known HLA epitope matching methods. He summarizes the clinical findings around HLA epitope mismatches and finally clears up common misunderstandings about epitope matching.
Special thanks to Omixon for inviting us to your webinar series.
Epitope Matching: There is no Excuse (In Collaboration with Omixon)
NOW PLAYING
Calculate Epitope Mismatch Probabilities with PIRCHE RAMP (In Collaboration with Immucor)
DESCRIPTION
In collaboration with our partners at Immucor, PIRCHE Director of Technology, Matthias Niemann, is on hand in this session from the virtual 2020 ASHI conference to walk you through the ins and outs of our exciting PIRCHE SOT RAMP (Solid Organ Transplantation Risk and Acceptable Mismatch Profile) module. What is RAMP? How does it work? What makes it so great? Watch this presentation to find out all of this and more.
Calculate Epitope Mismatch Probabilities with PIRCHE RAMP (In Collaboration with Immucor)
NOW PLAYING
Webinar 2021-02: “PIRCHE Epitope Matching in Kidney Transplantation: A Case Study ” (In Collaboration with GenDx)
DESCRIPTION
In this session, Eric Spierings, inventor of the PIRCHE concept, and Matthias Niemann, PIRCHE Director of Technology, introduce the epitope matching landscape, showing firstly how the PIRCHE algorithm integrates into the wider context of existing epitope matching models and secondly explaining what makes it different from other models with which you may or may not already be familiar.
To give you a practical insight into how PIRCHE matching is applied on a case by case basis in the solid organ transplantation setting, a case study is also presented to show how PIRCHE matching may be applied in kidney transplantation. The session is rounded out by presenting some recent insights into PIRCHE epitope matching.
Special thanks to GenDx for inviting us to your webinar series.
PIRCHE Epitope Matching in Kidney Transplantation A Case Study (In Collaboration with GenDx)
NOW PLAYING
What is PIRCHE – A Brief Handcrafted Story
DESCRIPTION
The human immune system is amazing! Here we explain the major components of epitope matching and why they are important in transplantation medicine.
What is PIRCHE - A Brief Handcrafted Story
NOW PLAYING
To PIRCHE or Not to PIRCHE
DESCRIPTION
In this webinar hosted by our partner Immucor, NYU Langone Transplant Institute’s Immunogenetics Laboratory Director, Massimo Mangiola discusses the PIRCHE technology, its applications and its impact on the future of transplantation diagnostics.
To PIRCHE Or Not To PIRCHE
NOW PLAYING
DESCRIPTION
Pirche Quarterly Webinar 1 (April 2023)
NOW PLAYING
Episode 7 of our Webinar Series 2019
DESCRIPTION
In this episode we cover:
- How to apply the PIRCHE batch matching modules
- How to read generated files in R and plot PIRCHE scores
